This will facilitate venous return, which should normally occur due to contraction of calf muscles in an ambulant person. The device provides intermittent inflation and deflation of the cuffs so that intermittent compression is applied. Intermittent pneumatic compression have cuffs applied to the legs and tubings attached to a motorised device. The number needed to prevent one deep vein thrombosis was 11 while that for pulmonary embolism was 63 with intermittent pneumatic compression. Combining pharmacological DVT prophylaxis and intermittent pneumatic compression further reduces the risk DVT (relative risk, 0.54 P=0.02). Intermittent pneumatic compression was found to be as effective as pharmacological thromboprophylaxis, with an added advantage of lower bleeding risk (relative risk, 0.41 P<0.01). It was also more effective than thromboembolic deterrent stockings. Pulmonary embolism was reduced to 1.2% from 2.8%, that is an absolute risk reduction of 1.6% (relative risk, 0.48 P<0.01). Intermittent pneumatic compression reduced the risk of deep vein thrombosis from 16.7% to 7.3%. They also checked the additional benefit of adding pharmacological thromboprophylaxis. The authors analyzed data from over sixteen thousand patients in seventy clinical trials to assess the benefit of giving intermittent pneumatic compression of the lower limbs in preventing DVT. The risk of DVT (deep vein thrombosis) and pulmonary embolism can be reduced by giving intermittent pneumatic compression of the calf muscles. Intermittent pneumatic compression for DVT prevention
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